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Adenomyosis — Specialist Diagnosis and Treatment

Comprehensive assessment and individualised management of adenomyosis, combining advanced diagnostics with minimally invasive surgical and medical treatment options.

At a Glance: Adenomyosis

Adenomyosis is a condition in which tissue similar to the lining of the uterus (endometrium) grows into the muscular wall of the uterus (myometrium). This causes the uterus to enlarge and can lead to heavy, painful periods and chronic pelvic pain. Adenomyosis is common and can occur on its own or alongside other conditions such as endometriosis and fibroids.

  • Heavy or prolonged menstrual bleeding
  • Severe menstrual cramps (dysmenorrhoea)
  • Chronic pelvic pain
  • Pain during intercourse
  • A feeling of pelvic pressure or fullness
  • Bloating, particularly around the time of menstruation

What Is Adenomyosis

Adenomyosis is a condition in which tissue similar to the lining of the uterus (endometrium) grows into the muscular wall of the uterus (myometrium). This causes the uterus to enlarge and can lead to heavy, painful periods and chronic pelvic pain. Adenomyosis is common and can occur on its own or alongside other conditions such as endometriosis and fibroids.

  • Heavy or prolonged menstrual bleeding
  • Severe menstrual cramps (dysmenorrhoea)
  • Chronic pelvic pain
  • Pain during intercourse
  • A feeling of pelvic pressure or fullness
  • Bloating, particularly around the time of menstruation

Who Is Affected

Adenomyosis can affect women of any age during their reproductive years, although it is more commonly diagnosed in the thirties and forties. It frequently coexists with endometriosis and fibroids, and may be a contributing factor in cases of unexplained heavy bleeding or pelvic pain.

Diagnosis Approach

Adenomyosis was historically only diagnosed after hysterectomy, but advances in imaging now allow for accurate non-invasive diagnosis. Prof Mahmood uses a structured approach to assessment.

  • Detailed symptom and menstrual history
  • Clinical examination
  • Transvaginal ultrasound with specific assessment for adenomyosis features
  • MRI for detailed evaluation where indicated
  • Exclusion of other conditions such as fibroids, endometriosis, and endometrial pathology

Prof Mahmood's Approach

Prof Uzma Mahmood provides expert assessment and management of adenomyosis, with an understanding that this condition is frequently underdiagnosed and often coexists with other pelvic conditions. She ensures that each patient receives an accurate diagnosis and a management plan that reflects their symptoms, reproductive goals, and personal preferences.

  • Expert imaging assessment and accurate diagnosis
  • Clear explanation of the condition and treatment options
  • Individualised management planning
  • Assessment for coexisting conditions (endometriosis, fibroids)
  • Minimally invasive surgical expertise when surgery is required

Treatment Options

Treatment depends on the severity of symptoms, the extent of adenomyosis, and the patient's reproductive wishes and preferences.

Non-Surgical Management

Many patients with adenomyosis can be effectively managed with medical treatment, particularly when symptoms are mild to moderate or when fertility preservation is a priority.

  • Levonorgestrel intrauterine system (Mirena coil)
  • Hormonal treatments (combined pill, progestogens, GnRH analogues)
  • Non-steroidal anti-inflammatory drugs for pain
  • Tranexamic acid for heavy bleeding
  • Iron supplementation for anaemia

Surgical Management

When medical treatment is insufficient or not appropriate, surgical options are considered. Prof Mahmood specialises in minimally invasive approaches.

  • Laparoscopic or robotic-assisted hysterectomy (definitive treatment)
  • Adenomyomectomy (excision of adenomyosis with uterine preservation) in selected cases
  • Combined procedures where adenomyosis coexists with endometriosis or fibroids

When to Seek Help

You should consider specialist assessment if you experience any of the following. Adenomyosis is a treatable condition, and an accurate diagnosis is the first step towards effective management.

  • Progressively worsening period pain
  • Heavy or prolonged menstrual bleeding
  • Chronic pelvic pain that is not improving
  • Pain during intercourse
  • Symptoms of anaemia despite treatment
  • A diagnosis of adenomyosis on imaging that has not been fully assessed

Frequently Asked Questions

Adenomyosis is a condition where tissue similar to the womb lining grows into the muscular wall of the uterus. This causes the uterus to enlarge and can result in heavy, painful periods and chronic pelvic pain. It is a common condition that can occur on its own or alongside endometriosis and fibroids.

Adenomyosis can now be accurately diagnosed using transvaginal ultrasound and MRI, without the need for surgery. Prof Mahmood uses specialist imaging assessment to identify the characteristic features of adenomyosis and to exclude other conditions.

No. While both conditions involve tissue similar to the uterine lining, in adenomyosis the tissue grows into the muscular wall of the uterus, whereas in endometriosis it grows outside the uterus. The two conditions frequently coexist and can cause similar symptoms, but they are distinct conditions requiring different management strategies.

Yes. Many patients can be effectively managed with medical treatment such as the Mirena coil, hormonal therapies, and pain management. In selected cases, adenomyomectomy (surgical excision of adenomyosis while preserving the uterus) may be an option. Hysterectomy is considered for severe cases that have not responded to other treatments.

Adenomyosis may affect fertility and has been associated with reduced implantation rates and an increased risk of miscarriage. However, many women with adenomyosis conceive successfully. Prof Mahmood will discuss the potential impact on fertility and appropriate management options during the consultation.

Adenomyosis is an oestrogen-dependent condition, and symptoms typically improve after menopause as oestrogen levels decline. For women who are premenopausal and experiencing significant symptoms, effective treatment options are available to manage the condition until menopause occurs naturally.

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